Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here for more information

Click here to sign up for SAGE Journal Email Alerts today!

Sign In to gain access to subscriptions and/or personal tools.
Clinical Pediatrics
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
0009922808316988v1
47/8/817    most recent
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Greenberg, R. A.
Right arrow Articles by Roosevelt, G. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Greenberg, R. A.
Right arrow Articles by Roosevelt, G. E.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

A Comparison of Oral Dexamethasone With Oral Prednisone in Pediatric Asthma Exacerbations Treated in the Emergency Department

Richard A. Greenberg, MD

Department of Pediatrics, Division of Pediatric Emergency Medicine, University of Utah School of Medicine, Salt Lake City, Utah, richard.greenberg{at}hsc.utah.edu

Gwen Kerby, MD

Section of Pulmonary Medicine University of Colorado at Denver and Health Sciences Center, The Children' s Hospital

Genie E. Roosevelt, MD, MPH

Section of Emergency Medicine University of Colorado at Denver and Health Sciences Center, The Children's Hospital, Denver, Colorado

The aim of this study was to determine if 2 doses of oral dexamethasone are as effective as a 5-day course of oral prednisone in preventing relapse for pediatric asthma exacerbations. Patients presenting to the emergency department with an asthma exacerbation were randomized to receive 0.6 mg/kg of dexamethasone or 2 mg/kg of prednisone in a prospective, double-blind study. The primary outcome was relapse within 10 days, and the secondary outcome was vomiting in the emergency department. Eighty-nine patients completed the study: 38 in the prednisone group and 51 in the dexamethasone group. In all, 3 patients in the prednisone group (8%) and 8 patients in the dexamethasone group (16%) required an unscheduled follow-up visit (P = .27). In all, 7 patients in the prednisone group (18%) and 5 patients in the dexamethasone group (10%) had vomiting ( P = .24). No difference was found in the relapse rate or incidence of vomiting between patients given prednisone and dexamethasone for pediatric asthma exacerbations.

Key Words: pediatric • asthma • prednisone • dexamethasone

This version was published on October 1, 2008

Clinical Pediatrics, Vol. 47, No. 8, 817-823 (2008)
DOI: 10.1177/0009922808316988
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 cfpHome page
A. E. Shefrin and R. D. Goldman
Use of dexamethasone and prednisone in acute asthma exacerbations in pediatric patients
Can Fam Physician, July 1, 2009; 55(7): 704 - 706.
[Abstract] [Full Text] [PDF]