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Clinical Pediatrics
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Excessive Growth

Vasudha Narayanaswamy, MD

University of South Alabama Children's and Women's Hospital, Mobile

Kenneth R. Rettig, MD

Division of Pediatric Endocrinology, University of South Alabama Medical Center, Mobile

Samar K. Bhowmick, MD, FACE

Division of Pediatric Endocrinology, University of South Alabama Medical Center, Mobile, sbhowmick{at}usouthal.edu

Tall stature and excessive growth syndrome are a relatively rare concern in pediatric practice. Nevertheless, it is important to identify abnormal accelerated growth patterns in children, which may be the clue in the diagnosis of an underlying disorder. We present a case of pituitary gigantism in a 2 1/2-year-old child and discuss the signs, symptoms, laboratory findings, and the treatment. Brief discussions on the differential diagnosis of excessive growth/tall stature have been outlined. Pituitary gigantism is very rare in the pediatrics age group; however, it is extremely rare in a child that is less than 3 years of age. The nature of pituitary adenoma and treatment options in children with this condition have also been discussed.

Key Words: excessive growth • growth hormone • insulin-like growth factor-1 • insulin growth factor binding protein 3 • pituitary macroadenoma

This version was published on September 1, 2008

Clinical Pediatrics, Vol. 47, No. 7, 705-710 (2008)
DOI: 10.1177/0009922807311740
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