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Clinical Pediatrics
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What's this?

Use of Intranasal Corticosteroids in the Management of Congestion and Sleep Disturbance in Pediatric Patients With Allergic Rhinitis

Bob Q. Lanier, MD

Division of Immunology, University of North Texas Health Science Center, Fort Worth, Texas, boblaniermd{at}askdrbob.com

Allergic rhinitis affects a large number of children and exerts a considerable socioeconomic impact. It is underdiagnosed and inadequately treated, which predisposes children to potentially serious comorbidities. Allergic rhinitis symptoms may create nighttime breathing problems and sleep disturbances and have a negative effect on a child's ability to learn in the classroom. Although antihistamines have shown efficacy in relieving many symptoms, they have little effect on nasal congestion. This article summarizes the advantages of intranasal corticosteroids, including their effectiveness against congestion and excellent safety profile. Intranasal corticosteroids with minimal systemic bioavailability provide topical drug delivery that minimizes the potential for systemic side-effects.

Key Words: allergic rhinitis • children • intranasal corticosteroids

This version was published on June 1, 2008

Clinical Pediatrics, Vol. 47, No. 5, 435-445 (2008)
DOI: 10.1177/0009922807310249
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