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Clinical Pediatrics
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X-linked Hypophosphatemic Rickets Associated With Respiratory Failure

Andrea Balazs, MD

Department of Pediatric Endocrinology and Metabolism, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, aebalazs{at}texaschildrenshospital.org

George Jeha, MD

Department of Pediatric Endocrinology and Metabolism, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas

Sheila K. Gunn, MD

Department of Pediatric Endocrinology and Metabolism, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas

Lefkothea P. Karaviti, MD, PhD

Department of Pediatric Endocrinology and Metabolism, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas

We report a 5-year-old girl who presented to our emergency room with respiratory arrest and limb deformities and was subsequently diagnosed with X-linked hypophosphatemic rickets. On normalization of the serum phosphorus concentration, her respiratory distress resolved, illustrating that untreated X-linked hypophosphatemic rickets can lead to life-threatening respiratory distress.

Key Words: hypophosphatemia • respiratory arrest • hypophosphatemic disorder • PHEX

This version was published on April 1, 2008

Clinical Pediatrics, Vol. 47, No. 3, 293-295 (2008)
DOI: 10.1177/0009922807308174
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