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Clinical Pediatrics
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Rapid Detection and Identification of Mucopolysaccharides in Urine

T.P. McDonald, PH.D.

the University of Tennessee Memorial Research Center and Hospital, 1924 Alcoa Highway, Knoxville, Tenn. 37920

Carmen Lozzio, M.D.

the University of Tennessee Memorial Research Center and Hospital, 1924 Alcoa Highway, Knoxville, Tenn. 37920

Pauline Lotkin, M.T.

the University of Tennessee Memorial Research Center and Hospital, 1924 Alcoa Highway, Knoxville, Tenn. 37920

This technic decreases the time required for MPS (mucopolysaccharide) testing, and per mits quantitative measurement of urinary MPS without the need for elaborate electrophoretic and chromato graphic equipment. The method, if supplemented by a differential chromato graphic study, helps identify specific fractions of the MPS components. These two screening methods are useful for confirmation of clinical diagnosis of various mucopolysaccharidoses.

Clinical Pediatrics, Vol. 9, No. 5, 272-276 (1970)
DOI: 10.1177/000992287000900511
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