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Clinical Pediatrics
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*Liver Diseases
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Cystic Disease of Liver and Kidney with Portal Hypertension

A Cause of Sudden Unexpected Hematemesis

William D. Bradford

Department of Pathology, Duke University Medical Center, Durham, North Carolina 27706

John W. Bradford

Department of Pathology, Duke University Medical Center, Durham, North Carolina 27706

Stanley Porter

Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27706

James B. Sidbury, JR

Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27706

Cystic disease of the liver and kidney has a genetic basis, and is more frequent in females. When portal hypertension accom panies this malformation the patient often presents with sudden, unexpected hemateme sis.

Severe or unusual infections, difficult to treat, represent other problems for the clini cian. One of the two patients here described was found at autopsy to have superimposed signs of cytomegalic inclusion disease in lungs and liver.

Clinical Pediatrics, Vol. 7, No. 5, 299-306 (1968)
DOI: 10.1177/000992286800700515
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