This Article Full Text (PDF) All Versions of this Article: 0009922809340432v1 48/8/844    most recent References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Scopus Google Scholar Articles by Kitsommart, R. Articles by Paes, B. PubMed PubMed Citation Articles by Kitsommart, R. Articles by Paes, B. Social Bookmarking                         What's this?

Outcomes of Late-Preterm Infants: A Retrospective, Single-Center, Canadian Study

Neonatology Division, Siriraj Hospital Mahidol University, Bangkok, Thailand, Neonatology Division, McMaster University, Hamilton, Ontario, Canada

Marianne Janes, MHSc

Neonatology Division, McMaster University, Hamilton, Ontario, Canada

Vikas Mahajan, MD

Neonatology Division, McMaster University, Hamilton, Ontario, Canada

Asad Rahman, MD

Neonatology Division, McMaster University, Hamilton, Ontario, Canada

Wendy Seidlitz, MSc

McMaster Children's Hospital, Hamilton Health Sciences, Hamilton, Ontario, Canada

Jennifer Wilson, MHSc

Neonatology Division, McMaster University, Hamilton, Ontario, Canada

Bosco Paes, MBBS, FRCPI, FRCPC

McMaster Children's Hospital, Hamilton Health Sciences, Hamilton, Ontario, Canada, paes{at}mcmaster.ca

Objective. To study the prevalence of major morbidities and mortality of inborn, late-preterm infants. Methods. A retrospective review was conducted from 2004 to 2008. Descriptive outcomes were compared with predefined aggregate outcomes of term infants during the same period. Results. Data on 1193 late-preterm and 8666 term infants were compared. Majority of late-preterm infants were 36 weeks (43.6%), followed by 35 weeks (29.2%) and 34weeks (27.2%), respectively. The prevalence of intensive care admission, respiratory support, pneumothorax, and mortality in late preterm infants was significantly higher compared with term infants. Mechanical ventilation and continuous positive airway pressure rates substantially decreased with increased gestational age. Although only 1.0% had positive cultures, 28.5% received parenteral antibiotics. The late-preterm group had a 12-fold higher risk of death with an overall mortality rate of 0.8%. Conclusion. This study confirmed the high-risk status of late-preterm infants with worse mortality and morbidities compared with term infants.

Key Words: late preterm • outcomes • perinatal • morbidity • mortality

This version was published on October 1, 2009

Clinical Pediatrics, Vol. 48, No. 8, 844-850 (2009)
DOI: 10.1177/0009922809340432


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?