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Is Environmental Tobacco Smoke Exposure a Risk Factor for Acute Gastroenteritis in Young Children?

Virginia Commonwealth University School of Medicine, Richmond, Virginia, pkumnji{at}vcu.edu

Carole L. Mangrem, MD

Children's Clinic of Clarksdale, Clarksdale, Mississippi

Peggy J. Wells, MD

Children's Clinic of Clarksdale, Clarksdale, Mississippi

Henry G. Herrod, MD

Department of Pediatrics, University of Tennessee Health Science Center and the Urban Child Institute, Memphis, Tennessee

Because passive smoke exposure has not been previously linked to diarrhea diseases in children, it was hypothesized that very young children exposed to environmental tobacco smoke (ETS) exposure at home would also be more likely to develop infectious gastroenteritis (GE) than their unexposed counterparts. During 1-year period, 260 children 36 months and younger were prospectively followed up in a private pediatric practice in a southern community in the United States. Multiple logistic regression analysis showed that ETS was strongly predictive of acute GE in the univariate analysis (P = .003). Even after controlling for the various confounders, ETS exposure was still significantly associated with acute GE (relative risk = 2.55; 95% CI = 1.26-5.18). It is speculated that, similar to acute respiratory infections, the same mechanisms may explain why ETS may also be associated with acute infectious GE.

Key Words: infectious diarrhea • ETS exposure • risk factors • nicotine

This version was published on September 1, 2009

Clinical Pediatrics, Vol. 48, No. 7, 756-762 (2009)
DOI: 10.1177/0009922809332591


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