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Recurrent Fever and Rash

Carman and Adams Department of Pediatrics, Children's Hospital of Michigan, Detroit, Michigan

Deepak Kamat, MD, PhD

Carman and Adams Department of Pediatrics, Children's Hospital of Michigan, Detroit, Michigan, dkamat{at}med.wayne.edu

Periodic fever is uncommon in children. The differential diagnosis is large, even though associated symptoms such as rash may help narrow the differential diagnosis. Atypical presentations require thoughtful evaluation. This article describes a case of a 4-year-old boy who presented to the emergency department with recurrent fever, vomiting, abdominal pain, myalgias, and rash. His hospital course is described along with a review on the background, evaluation, management, and complications of tumor necrosis receptor-1 alpha periodic syndrome.

Key Words: tumor necrosis receptor-1 alpha periodic syndrome • rash • periodic fever • familial Mediterranean fever • Henoch—Schonlein purpura • abdominal pain

This version was published on July 1, 2009

Clinical Pediatrics, Vol. 48, No. 6, 679-682 (2009)
DOI: 10.1177/0009922809333090


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