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Clinical Pediatrics
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Clinical Spectrum of Shiga Toxin–Producing Escherichia coli (STEC) in Adults and Children

Stephanie Simon Appleman, MD

Department of Pediatrics, INOVA Fairfax Hospital for Children, Falls Church, Virginia, stephanie_appleman{at}yahoo.com

David Ascher, MD, MBA

Department of Pediatrics, INOVA Fairfax Hospital for Children, Falls Church, Virginia

Choong Park, PhD

Department of Microbiology, INOVA Fairfax Hospital for Children, Falls Church, Virginia

This report describes the clinical spectrum of disease among a series of pediatric and adult patients with symptoms of gastroenteritis that subsequently tested positive for Shiga toxin—producing Escherichia coli in their stool. All diarrheal stools (n = 1712) between July 2005 and November 2006 were tested with Premier EHEC (Meridian Bioscience, Cincinnati, OH). A total of 1.6% patients (27/1712) tested positive and 41% of patients had non-0157 E. coli, which can cause moderate disease requiring hospitalization. Cases of non-0157 E. coli would have been missed without testing for Shiga toxin. All bloody stools, and perhaps all stools, should be tested for Shiga toxin.

Key Words: Shiga toxin • STEC • E. coli 0157 • E. coli non-0157 • gastroenteritis

This version was published on January 1, 2009

Clinical Pediatrics, Vol. 48, No. 1, 99-102 (2009)
DOI: 10.1177/0009922808321901
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