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Clinical Pediatrics
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Reviews

Cutaneous Mastocytosis: A Review Focusing on the Pediatric Population

Laura D. Briley, MD

PGY3- Department of Dermatology Brody Schol Medicine at East Carolina University, Brileyla{at}ecu.edu

Charles M. Phillips, MD

Division Chief of Dermatology Brody School of Medicine at East Carolina University, Greenville, North Carolina

Cutaneous mastocytosis can be divided into 4 different clinical variants—urticaria pigmentosa, solitary mastocytoma, diffuse cutaneous mastocytosis, and telangiectasia macularis eruptiva perstans. Skin findings are often accompanied by symptoms secondary to mast cell release of mediators. These symptoms can be both localized to the skin lesion and systemic because of the release of mediators into the bloodstream. The majority of pediatric cases of cutaneous mastocytosis show a good prognosis with gradual resolution of both symptoms and skin lesions. This article will review each of the 4 clinical presentations focusing on pediatric-onset of disease while reviewing the literature.

Key Words: mastocytosis • mast cell disease • urticaria pigmentosa • mastocytoma

This version was published on October 1, 2008

Clinical Pediatrics, Vol. 47, No. 8, 757-761 (2008)
DOI: 10.1177/0009922808318344
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