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Clinical Pediatrics
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Transdermal Patch Medication Delivery Systems and Pediatric Poisonings, 2002-2006

Dina Parekh, MD

Department of Pediatrics and Emergency Medicine, Darnall Army Medical Center, Ft Hood

Michael A. Miller, MD

Department of Pediatrics and Emergency Medicine, Darnall Army Medical Center, Ft Hood, Central Texas Poison Control Center, Temple, Department of Emergency Medicine, Tripler Army Medical Center, Honolulu, Hawaii, michael.adam.miller{at}us.army.mil

Doug Borys, PharmD

Central Texas Poison Control Center, Temple

Paresh R. Patel, MD

Department of Pediatrics and Emergency Medicine, Darnall Army Medical Center, Ft Hood

Marc E. Levsky, MD

Department of Pediatrics and Emergency Medicine, Darnall Army Medical Center, Ft Hood

Transdermal drug delivery systems are an increasingly popular method of medication delivery containing large quantities of medication and presenting new opportunities for toxicity. To provide a description of exposures to transdermal medications in a pediatric population, we studied exposures in individuals less than 12 years of age. This is a retrospective database study in which the Texas Poison Center Network database from 2002 to 2006 was reviewed. In all, 336 poison control center records of patch exposures over the 5-year period were identified. Of those, 110 cases involved children less than 12 years old. A majority of cases resulted in no significant clinical effects. One death resulted from opioid toxicity. Although a majority of patch exposures in children less than 12 years of age resulted in no significant clinical toxicity, practitioners and the public must be made aware of the available patch-based medications and their potential for toxicity in children.

Key Words: poisoning • pediatric • patch • transdermal

This version was published on September 1, 2008

Clinical Pediatrics, Vol. 47, No. 7, 659-663 (2008)
DOI: 10.1177/0009922808315211
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