Clinical Pediatrics

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

SAGETRACK

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Google Scholar
Right arrow Articles by Myers, C.
Right arrow Articles by Gervaix, A.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Myers, C.
Right arrow Articles by Gervaix, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Clinical Pediatrics, Vol. 47, No. 5, 493-495 (2008)
DOI: 10.1177/0009922807310936

Use of the Rapid Antigenic Test to Determine the Duration of Isolation in Infants Hospitalized for Respiratory Syncytial Virus Infections

Catherine Myers, MD

Department of Pediatrics, University Hospital of Geneva, catherine.myers{at}hcuge.ch

Noemie Wagner, MD

Department of Pediatrics, University Hospital of Geneva

Laurent Kaiser, MD, PhD

Department of Infectious Diseases, University Hospital of Geneva, Geneva, Switzerland

Klara Posfay-Barbe, MD

Department of Pediatrics, University Hospital of Geneva

Alain Gervaix, MD, PhD

Department of Pediatrics, University Hospital of Geneva

Infants hospitalized for bronchiolitis associated with respiratory syncytial virus are isolated for the duration of their hospitalization. This article reviews whether a negative rapid antigenic test could be used to shorten the duration of isolation measures. Rapid respiratory syncytial virus tests were performed from day 3 on alternate days in all patients hospitalized for bronchiolitis. Isolation measures were removed when the test result was negative. The result of the antigenic test was confirmed by viral culture and polymerase chain reaction. Surveillance of nosocomial cases was performed daily. Forty-one patients were analyzed. On day 3, 51.2% of patients were negative by viral culture and 56.1% were negative by rapid testing. On day 5, a further 26.8% were negative by viral culture and 31.7% by rapid testing. The rapid antigen test had a low sensitivity at 60% and a specificity of 76% compared with viral cultures; therefore this test alone cannot be used to lift isolation measures.

Key Words: respiratory syncytial virus • contagiousness • antigenic testing.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?