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Clinical Pediatrics
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Mercury Intoxication: Lack of Correlation Between Symptoms and Levels

Jyothsna Gattineni

Department of Pediatrics, University of Texas

Susan Weiser

Department of Pediatrics, University of Texas

Amy M. Becker

Department of Pediatrics, University of Texas

Michel Baum

Department of Pediatrics, University of Texas, Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, Michel.Baum{at}UTSouthwestern.edu

The incidence of mercury intoxication has decreased considerably because of stricter public health regulations. However, it has not been completely eliminated and should be considered in a child with unexplained tachycardia, hypertension, mood changes, weight loss, and acrodynia. Mercury intoxication can be difficult to differentiate from pheochromocytoma and Kawasaki's disease. Here, the authors report the case of an 8-year-old boy with history of mercury exposure, signs and symptoms suggestive of mercury intoxication, and good response to chelation therapy, but with only mild increase in urinary mercury levels. This case highlights the fact that urinary mercury levels do not necessarily correlate with the severity of clinical signs and symptoms of mercury intoxication.

Key Words: acrodynia • hypertension • catecholamines • elemental mercury

This version was published on December 1, 2007

Clinical Pediatrics, Vol. 46, No. 9, 844-846 (2007)
DOI: 10.1177/0009922807303893
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