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This version was published on December 1, 2007
Clinical Pediatrics, Vol. 46, No. 9, 842-843 (2007)
DOI: 10.1177/0009922807303546
© 2007 SAGE Publications

Bleeding After Circumcision in a Newborn Receiving Sildenafil

David Gamboa, MD

Children's Hospital & Research Center, Oakland, Calfornia, dgamboa{at}mail.cho.org

Daniel Robbins, MD

Lamorinda Pediatrics, Lafayette, California

Ziad Saba, MD

Department of Cardiology, Children's Hospital & Research Center, Oakland, California

This report describes a case of bleeding as a complication of circumcision in a 2-week-old infant being treated with sildenafil for persistent pulmonary hypertension of the newborn. The vasodilatory effects of sildenafil on the penile vasculature may have contributed to the postoperative bleeding in this patient.

Key Words: persistent pulmonary hypertension of the newborn • sildenafil • pulmonary vascular resistance • phosphodiesterase type 5 • circumcision


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