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Clinical Pediatrics
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Recurrent Neonatal Group B Streptococcal Disease Associated With Infected Breast Milk

Lin-Yu Wang, MD

Department of Pediatrics, Chi-Mei Foundation Medical Center, Tainan, Taiwan

Chun-Ta Chen, MD

Department of Pediatrics, Chi-Mei Foundation Medical Center, chenped@ yahoo.com.twTainan, Taiwan

Won-Hsiung Liu, MD

Department of Pediatrics, Chi-Mei Foundation Medical Center, Tainan, Taiwan

Yin-Hsuan Wang, MA

Department of Clinical Pathology, Chi-Mei Foundation Medical Center, Tainan, Taiwan

Group B streptococcus (GBS) is a major cause of severe systemic infections among the newborn. Both recurrent and maternal mastitis-associated, group B streptococcus diseases are uncommon. Persistence of GBS colonization of infants' mucous membrane is postulated to influence the pathogeneses of recurrent GBS infection. The authors describe a term infant who was treated for GBS sepsis and meningitis and then later developed recurrent GBS sepsis, without meningitis, due to feeding of infected breast milk. Randomly amplified polymorphic DNA polymerase chain reaction assay was performed to demonstrate that the GBS isolates from the first and second episode of infection and the maternal milk are identical. The authors conclude that transmission of GBS through breast milk should be considered in cases of recurrent neonatal GBS infection and bacterial culture of breast milk should be routinely performed in such cases.

Key Words: group-B streptococcus • breast milk • infection

Clinical Pediatrics, Vol. 46, No. 6, 547-549 (2007)
DOI: 10.1177/0009922807299467
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