Clinical Pediatrics

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Register here to gain access to SAGE's 500+ Journals Online

Click here to sign up for SAGE Journal Email Alerts today!

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rush, D. E.
Right arrow Articles by Malian, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rush, D. E.
Right arrow Articles by Malian, M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Clinical Pediatrics, Vol. 46, No. 2, 154-159 (2007)
DOI: 10.1177/0009922806289431

Clindamycin Versus Unasyn in the Treatment of Facial Cellulitis of Odontogenic Origin in Children

Demetris E. Rush, DDS

Children’s Hospital of Michigan and Wayne State University, Detroit, Michigan

Nahed Abdel-Haq, MD

Children’s Hospital of Michigan and Wayne State University, Detroit, Michigan

Jian-Fu Zhu, DDS, MSD, DSc

Children’s Hospital of Michigan and Wayne State University, Detroit, Michigan, Jianfuz{at}aol.com

Basim Aamar, MD

Children’s Hospital of Michigan and Wayne State University, Detroit, Michigan

Monica Malian, RPH

Children’s Hospital of Michigan and Wayne State University, Detroit, Michigan

The study was undertaken to characterize the microbiology of dental abscesses in children and to compare clindamycin and ampicillin/sulbactam in the treatment of facial cellulitis of odontogenic origin. Sixty children with acute facial cellulitis of dental origin underwent surgery (extraction or root canal procedure) within 24 hours of presentation. Pus samples were cultured aerobically and anaerobically. Patients were randomized (1:1) to receive intravenous ampicillin/sulbactam or clindamycin for 48 hours followed by oral amoxicillin/clavulanate or clindamycin for 7 days. A total of 211 bacterial isolates were recovered from 54 samples. The most common aerobic and facultative organisms were viridans streptococci, Neisseria, and Eikenella species. Among anaerobes, Prevotella and Peptostreptococcus species were the most frequent. No treatment failure occurred in either group. Dental abscesses in children are polymicrobial aerobic/anaerobic infections. Treatment of complicated dental infections with ampicillin plus a ß-lactamase inhibitor or clindamycin in combination with surgical drainage is very effective.

Key Words: clindamycin • Unasyn • dental • cellulitis • abscess • children


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?