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Clinical Pediatrics
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Absence of Tooth Staining With Doxycycline Treatment in Young Children

Benjamin Volovitz, MD

Department of Pediatrics C, Asthma Clinic, Schneider Children’s Medical Center of Israel, Petah Tiqwa, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Benjamin{at}Volovitz.com

Ronit Shkap, DMD

Department of Oral and Maxillofacial Surgery, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel

Jacob Amir, MD

Department of Pediatrics C, Schneider Children’s Medical Center of Israel, Petah Tiqwa, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv

Shlomo Calderon, DMD

Department of Oral and Maxillofacial Surgery, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel

Izhak Varsano, MD

Department of Pediatrics C, Asthma Clinic, Schneider Children’s Medical Center of Israel, Petah Tiqwa, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv

Moshe Nussinovitch, MD

Department of Pediatrics C, Schneider Children’s Medical Center of Israel, Petah Tiqwa, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv

The aim of the study was to determine if doxycycline causes tooth staining in young children. A dentist examined 31 randomized children who had been treated with doxycycline and 30 children who had not received doxycycline. Mean age of the children was 10.4 {mp} 2.1 years. Mean age at receipt of the first doxycycline treatment was 4.1 {mp} 1.6 years, and mean number of doxycycline courses was 2.0 {mp} 1.3. No tooth staining was detected by the dentist in any of the children in either group. These findings indicate that treatment with doxycycline in children aged 2 to 8 years is not associated with tooth staining.

Key Words: children • tooth-staining • asthma • doxycycline

Clinical Pediatrics, Vol. 46, No. 2, 121-126 (2007)
DOI: 10.1177/0009922806290026
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