Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here to register

Sign In to gain access to subscriptions and/or personal tools.
Clinical Pediatrics
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Nakamizo, M.
Right arrow Articles by Akazawa, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nakamizo, M.
Right arrow Articles by Akazawa, K.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Mental Development of Infants With Congenital Hypothyroidism: A Longitudinal Study

Makiko Nakamizo, MD

Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata City, Japan

Shin-ichi Toyabe, MD, PhD

Department of Medical Informatics, Niigata University Medical and Dental Hospital, Division of Pediatrics, Department of Homeostatic Regulation and Development, Niigata Graduate School of Medical and Dental Sciences, Niigata University, Niigata City, Japan

Tadashi Asami, MD, PhD

Department of Nursing, Niigata Seiryo University, Niigata City, Japan

Kouhei Akazawa, PhD

Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata City, Japan

The purpose of this study was to assess the relationship between the clinical findings before starting treatment and the development quotient in children treated for congenital hypothyroidism. Patients with congenital hypothyroidism (n = 129) were divided into favorable and unfavorable groups according to intellectual performance. Children with congenital hypothyroidism generally have a similar intellectual outcome to that of healthy children. However, a low birth weight, the presence of complications, and a high serum thyroid-stimulating hormone value are the risk factors for unfavorable cases, who consistently have a development quotient score of less than 100.

Key Words: congenital hypothyroidism • thyroid-stimulating hormone • developmental quotient score

Clinical Pediatrics, Vol. 46, No. 1, 53-58 (2007)
DOI: 10.1177/0009922806289326
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?