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Vitamin D Deficiency in a Healthy Group of Mothers and Newborn Infants

Division of Pediatric Endocrinology, Child Health Evaluation and Research Unit, University of Michigan, Ann Arbor, Michigan, joyclee{at}med.umich.edu

Jessica R. Smith, MD

Department of Pediatric Endocrinology, Children’s Hospital, Boston, Massachusetts

Barbara L. Philipp, MD

Boston University School of Medicine, Department of General Pediatrics, Boston Medical Center, Boston, Massachusetts

Tai C. Chen, PhD

Section of Endocrinology, Diabetes and Nutrition, Boston Medical Center, Boston, Massachusetts

Jeffrey Mathieu, MS

Section of Endocrinology, Diabetes and Nutrition, Boston Medical Center, Boston, Massachusetts

Michael F. Holick, MD, PhD

Section of Endocrinology, Diabetes and Nutrition, Boston Medical Center, Boston, Massachusetts

Plasma 25-hydroxyvitamin D was measured in 40 healthy, mostly Black, mother-infant pairs. Although a majority of mothers received a daily prenatal multivitamin, vitamin D deficiency (<30 nmol/L), was found in 50% of mothers and 65% of their newborn infants, with a positive correlation between maternal and infant plasma 25-hydroxyvitamin D concentrations. Maternal vitamin D deficiency may represent an important risk factor for the development of rickets in children.

Key Words: rickets • vitamin D deficiency • maternal • newborn • 25-hydroxyvitamin D

Clinical Pediatrics, Vol. 46, No. 1, 42-44 (2007)
DOI: 10.1177/0009922806289311


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