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Clinical Pediatrics, Vol. 43, No. 8, 725-727 (2004)
DOI: 10.1177/000992280404300806

Diagnostic Yield of Parathyroid Hormone Testing in Children Evaluated for Hypercalciuria

Christina Lo, MD

Department of Pediatrics, Division of Nephrology, Schneider Children’s Hospital of the North Shore-Long Island Jewish Health System

Yael Zucker

Department of Pediatrics, Division of Nephrology, Schneider Children’s Hospital of the North Shore-Long Island Jewish Health System

Bernard G. Gauthier, MB, BS, FRACP

Department of Pediatrics, Division of Nephrology, Schneider Children’s Hospital of the North Shore-Long Island Jewish Health System

Marcela Vergara, MD

Department of Pediatrics, Division of Nephrology, Schneider Children’s Hospital of the North Shore-Long Island Jewish Health System

Rachel Frank, RN

Department of Pediatrics, Division of Nephrology, Schneider Children’s Hospital of the North Shore-Long Island Jewish Health System

Suzanne Vento, RN

Department of Pediatrics, Division of Nephrology, Schneider Children’s Hospital of the North Shore-Long Island Jewish Health System

Howard Trachtman, MD

Department of Pediatrics, Division of Nephrology, Schneider Children’s Hospital of the North Shore-Long Island Jewish Health System

Hypercalciuria is a frequent cause of non-glomerular hematuria in pediatric patients. Because hypercalciuria can be secondary to primary hyperparathyroidism, measurement of serum parathyroid hormone (PTH) levels is often performed in children with this urinary abnormality. A retrospective chart review was performed to determine the diagnostic yield of PTH measurements when performed under these clinical circumstances. Over a 30-month period (January 1, 2001 to September 30, 2003), among 31 children who had a PTH determination, the level was elevated in 1 (3%) patient. Based on these findings and the serious nature of untreated primary hyperparathyroidism, serum PTH level should be measured in pediatric patients with newly diagnosed hypercalciuria.


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