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Thrombocytosis in Pediatric HIV Infection

Pennsylvania State University, Hershey Medical Center, Hershey, PA, and Children’s National Medical Center, Washington, DC

Thrombocytopenia has been extensively reported in association with HIV infection. Twenty-four children (6%) from a cohort of 400 children with platelet counts >500,000/mm³ were reviewed. All had symptomatic disease and 10 (42%) patients died. In 4 children the platelet count exceeded 700,000/mm³ and in 1 patient the platelet count was 1.5 million/mm³. There were no thrombotic complications, and no specific therapy was required for the thrombocytosis. Thus HIV-1 infection, a chronic viral infection, is another etiologic agent for thrombocytosis and is associated with severe disease.

Clinical Pediatrics, Vol. 43, No. 7, 627-629 (2004)
DOI: 10.1177/000992280404300707


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