This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Web of Science (5) Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Auh, J. S. Articles by Katz, B. Z. Search for Related Content PubMed PubMed Citation Articles by Auh, J. S. Articles by Katz, B. Z. Social Bookmarking                         What's this?

Retrospective Assessment of Subacute or Chronic Osteomyelitis in Children and Young Adults

Children’s Memorial Hospital, Chicago, IL, Northwestern University, Feinberg School of Medicine, Department of Pediatrics

Helen J. Binns, MD, MPH

Children’s Memorial Hospital, Chicago, IL, Northwestern University, Feinberg School of Medicine, Department of Pediatrics

Ben Z. Katz, MD

Children’s Memorial Hospital, Chicago, IL, Northwestern University, Feinberg School of Medicine, Department of Pediatrics

To identify factors associated with and to describe treatment outcomes of pediatric subacute or chronic osteomyelitis (S/CO), we retrospectively identified 52 patients with S/CO from January 1994 to November 1999 seen at a large pediatric hospital infectious disease clinic. S/CO was defined by the following: >10 days of clinical symptoms; radiographic, surgical, or pathologic changes consistent with S/CO; or relapse of prior osteomyelitis. Of these patients 63% were male, median age 9 years. Bones involved included vertebra (19% of subjects), femur (17%), finger (12%), humerus (10%), and tibia (8%). Sixty-five percent had at least 1 risk factor (most commonly hardware, neurologic disease or preceding trauma, sepsis, or surgery). Blood, bone, or wound aspirate cultures were positive in 67%, most commonly for Staphylococcus aureus. Erythrocyte sedimentation rate (ESR) was elevated in 88% of 41 patients at the time of diagnosis. Intravenous antibiotics were given for a median of 6 weeks and oral antibiotics for a median of 4.5 months. One child had a complication. In conclusion, consideration of S/CO should be high when predisposing factors are present. ESR may be useful for determining effectiveness and duration of therapy. With prolonged antibiotic therapy nearly all patients demonstrated resolution of disease.

Clinical Pediatrics, Vol. 43, No. 6, 549-555 (2004)
DOI: 10.1177/000992280404300607


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?