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Clinical Pediatrics, Vol. 42, No. 6, 553-556 (2003)
DOI: 10.1177/000992280304200611

Outcome of Overactive Bladder in Children

Stanley Hellerstein, MD

The University of Missouri School of Medicine at Kansas City, Missouri, The Children's Mercy Hospital, Kansas City, Missouri

Amy Ajans Zguta, MHA

Stipend as a summer intern from contingency research funds provided to Stanley Hellerstein as the Ernest L. Glasscock, MD, Chair in Pediatric Research

One hundred forty-four children with a clinical diagnosis of overactive bladder were observed for a mean of 3.15 ± 1.92 years. Initial management consisted of a behavioral modification program that included increased fluid intake, a timed voiding schedule and, if applicable, treatment of constipation. Those who failed to improve with the preceding intervention within 10 days to 2 weeks received an anticholinergic medication. Follow-up information was obtained by telephone. Caretakers and/or patients were asked a standard set of questions. The outcome with respect to urinary urgency, urinary frequency, daytime incontinence, posturing and urinary tract infections was recorded. After an average follow-up period of 3 years, 68 (47.2%) of the 144 children recovered from all symptoms of overactive bladder and 61 (42.4%) had decreased symptoms. Fifteen of the children, or 10.4%, still had all of the symptoms originally associated with overactive bladder. Children who had posturing as one of their symptoms had a significantly increased risk of urinary tract infection.


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