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Continuous pH Monitoring Using the Paratrend® 7 Inserted into a Peripheral Vein in a Patient with Shock and Congenital Lactic Acidosis

Tiffanie R. Johnson, MD

Joseph D. Tobias, MD

Departments of Child Health and Anesthesiology, The University of Missouri, Columbia, Missouri

The authors present a 25-year-old woman who was admitted to the ICU for treatment of shock, respiratory failure, and acidosis related to congenital lactic acidosis from pyruvate dehydrogenase deficiency. To aid in ongoing management of the metabolic acidosis, the Paratrend® blood gas monitoring sensor was inserted through a peripheral venous site to provide a continuous measurement of pH and partial pressure of carbon dioxide (Pco₂). With the venous insertion of the Paratrend®, a clinically useful correlation with arterial blood gas values was noted. Linear regression analysis of the pH values from the venous blood gas analyses and the Paratrend® monitor revealed r² = 0.71 with p = 0.001 and r² = 0.78 with a p = 0.0003 for the Pco₂ values. Our preliminary experience suggests that venous placement of the Paratrend® monitor can be used to provide clinically useful, continuous measurement of pH and Pco₂.

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