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Clinical Pediatrics
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*PARATHYROID HORMONE
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*Rickets
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What's this?

Stage I Vitamin D-Deficiency Rickets Mimicking Pseudohypoparathyroidism Type II

Tarak Srivastava, MD

Section of Nephrology and Bone and Mineral Disorders Clinic, The Children's Mercy Hospital, University of Missouri at Kansas City

Uri S. Alon, MD

Section of Nephrology and Bone and Mineral Disorders Clinic, The Children's Mercy Hospital, University of Missouri at Kansas City

The clinical presentation and biochemical features of stage I vitamin D-deficiency rickets (VDR) and pseudohypoparathyroidism (PHP) type II are quite similar. These 2 entities have therefore often been mistaken for one another. We report our experience with 2 cases of stage I VDR that were originally diagnosed as PHP type II. The report provides an insight into the pathophysiology of VDR and PHP and thus allows for better differentiation between the 2 disease entities. It has become essential for pediatricians to recognize VDR owing to its resurgence in developed countries.

Clinical Pediatrics, Vol. 41, No. 4, 263-268 (2002)
DOI: 10.1177/000992280204100411
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