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Clinical Pediatrics
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Effectiveness of Treatments for Nocturnal Enuresis in a Heterogeneous Population

Seth L. Schulman, MD

Department of Pediatrics, Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; Department of Urology, Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; Division of Nephrology, Children's Hospital of Philadelphia, 34th and Civic Center Blvd, Philadelphia, PA 19104

Yosef Colish

F. Christian von Zuben, MS

Christine Kodman-Jones, PhD

Department of Urology, Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

The objective of this study was to determine the effectiveness of various treatments for nocturnal enuresis in a large, diverse population of children. A retrospective cohort review of patients with nocturnal enuresis was undertaken. All patients selected treatment after a single visit that included a history, examination, and demonstration of treatments. Families were contacted 1 year later to determine what treatment they chose and whether their child still wet. Families primarily chose an alarm (31%), followed by desmopressin acetate (22%) and oxybutynin (9%). Some preferred no treatment (23%). Fifty-six percent of patients using the alarm were completely dry compared to 18% using desmopressin acetate (p&lt0.0001), 16% using oxybutynin, and 28% receiving no treatment. In a heterogeneous population 1 year after a single visit, children whose parents chose the nocturnal enuresis alarm were most likely to be completely dry.

Clinical Pediatrics, Vol. 39, No. 6, 359-364 (2000)
DOI: 10.1177/000992280003900606
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This article has been cited by other articles:


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 CLIN PEDIATRHome page
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Nocturnal Enuresis: Current Concepts
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