This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Weiss, H. E. Articles by Piecuch, R. E. Search for Related Content PubMed PubMed Citation Articles by Weiss, H. E. Articles by Piecuch, R. E. Social Bookmarking                   What's this?

A Critical Review of Cranial Ultrasounds: Is There a Closer Association Between Intraventricular Blood, White Matter Abnormalities or Cysts, and Cerebral Palsy?

Department of Neonatology, Fifth Floor, Santa Clara Valley Medical Center, 751 South Bascom Avenue, San Jose, CA 95128

Ruth B. Goldstein, MD

Department of Radiology, University of California, San Francisco, CA

Robert E. Piecuch, MD

Department of Pediatrics, University of California, San Francisco, CA

In an attempt to determine cranial ultrasonographic features of preterm infants with intraventricular hemorrhage (IVHI) and/or periventricular white matter abnormalities (PVWMA) that could serve as more specific predictors of cerebral palsy (CP), we reviewed the cranial sonograms of 34 infants with IVH and/or PVWMA. Fourteen of the 34 infants studied (41%) developed CP. One of five infants with grade III LVH alone developed CP. Eleven infants with PVWMA did not develop cysts and only two (18%) developed CP (p=0.0⁴). Of the 18 infants who went on to develop cysts, four had a small, discrete solitary cyst and 14 had large cystic areas. Three of the four with small cysts were neurologically normal, whereas only three of the 14 with large cysts were neurologically normal (p=0.04). Preterm infants with grade III IVH in the absence of any parenchymal lesion had a more favorable neurologic outcome than those with IVH and concomitant PVWMA. Infants with PVWMA in the presence or absence of IVH had much poorer neurologic prognoses. In infants with PVWM abnormalities, both the presence and extent of cystic lesions, though not their location, are the strongest predictors of long-term neurologic outcome.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				W. D. Rhine and F. G. Blankenberg Cranial Ultrasonography NeoReviews, January 1, 2001; 2(1): e3 - 11. [Full Text]