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Clinical Pediatrics, Vol. 38, No. 5, 279-285 (1999)
DOI: 10.1177/000992289903800505

Delayed Pubertal Growth Spurt and Normal Adult Height Attainment in Boys Receiving Long-term Alternate-day Prednisone Therapy

Cesare Polito, MD

Angela La Manna, MD

Maria Rosaria Papale, MD

Giuseppina Villani, MD

Department of Pediatrics, 3rd Pediatric Clinic, Second University of Naples, Naples, Italy

Statural growth to age ≥20 years was studied in 10 boys with glomerulonephritis who received alternate-day prednisone (mean 1.2 mg/kg) for at least 2 consecutive years during pubertal age. Peak growth velocity was delayed after age 15 years in six patients and it was less than 7 cm/year in five. However, after age 16, growth velocity was significantly (p 0.02) higher than expected and allowed patients to ultimately reach their genetic height potential.


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