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Clinical Pediatrics, Vol. 37, No. 9, 531-535 (1998)
DOI: 10.1177/000992289803700902

Pneumococcal Bacteremia and Focal Infection in Young Children

Stephen J. Teach, MD, MPH

Division of Emergency Medicine, Department of Pediatrics, Children's Hospital of Buffalo, State University of New York at Buffalo School of Medicine and Biomedical Sciences; Department of Emergency Medicine, Children's National Medical Center, Suite 1450, 111 Michigan Ave, NW, Washington, DC 20010

Diane M. Dryja, MT, CLS

Debra Tristram, MD

Division of Pediatric Infectious Diseases, Department of Pediatrics, Children's Hospital of Buffalo, State University of New York at Buffalo School of Medicine and Biomedical Sciences

We reviewed a consecutive case series of 178 immunocompetent children aged 3-36 months without central venous lines who had blood cultures positive for Streptococcus pneumoniae by either of paired broth and quantitative culture methods. The incidence of accompanying focal infection was significantly greater in patients with >10 colony-forming units (cfu)/mL than in patients with <10 cfu/mL (30.4% vs 12.9% respectively, p=0.04). No significant relationships existed between the magnitude of bacteremia and the age, gender, presenting temperature, interval until the blood culture turned positive, total peripheral blood white cell count, absolute neutrophil count, or absolute band count. Overall, the quantitative method detected 59/178 (33.1%) of the isolates, including five isolates (2.8%) that the broth method failed to detect.


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