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Clinical Pediatrics
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Treatment of NIDDM in Youth

Misao Owada

Department of Pediatrics, Nihon University Hospital, Tokyo, Japan

Yoshikazu Nitadori

Department of Pediatrics, Nihon University Hospital, Tokyo, Japan

Teruo Kitagawa

Department of Pediatrics, Nihon University Hospital, Tokyo, Japan

This study presents the characteristics of 20 children (17 female) with NIDDM who required oral hypoglycemic agent (OHA) therapy. A family history of NIDDM was present in 55%. None had islet cell antibodies (ICA) or glutamic acid decarboxylase (GAD) antibodies. Tolbutamide was the drug of choice; glibenclamide was introduced if glycemic control was not obtained after 2 to 3 months of tolbutamide therapy. Seven of the patients eventually required insulin therapy. Clin Pediatr. 1998;37:117-122

Clinical Pediatrics, Vol. 37, No. 2, 117-121 (1998)
DOI: 10.1177/000992289803700209
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