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Clinical Pediatrics, Vol. 37, No. 11, 659-664 (1998)
DOI: 10.1177/000992289803701103

Blood Pressure in Children Exposed Prenatally to Cocaine

Robert Needlman, MD

Department of Pediatrics, Case Western Reserve University School of Medicine and Rainbow Babies and Children's Hospital, Cleveland, OH

Deborah A. Frank, MD

Howard Cabral, MPH

Mark Mirochnick, MD

Department of Pediatrics, Boston University School of Medicine and Boston Medical Center, Boston, MA

Christopher Kwon, MD

Department of Surgery, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, Ohio

Barry Zuckerman, MD

Department of Pediatrics, Boston University School of Medicine and Boston Medical Center, Boston, MA

Prenatal exposure to cocaine may alter autonomic nervous system function resulting in hypertension. Blood pressure was measured oscillometrically in a convenience sample of cocaine-exposed (n=32) and nonexposed (n=23) children, aged 8 to 26 months, by examiners unaware of exposure status. The exposed and nonexposed groups did not differ in systolic pressure (mean ± SD 102.3 ± 9.9 mm Hg vs 101.8 ± 8.1, respectively), diastolic pressure (45.7 ± 13.6 vs 51.7 ± 10.6), or pulse rate (113.0 ± 19.7 vs 119.1 ± 19.4). Prenatal exposure to cocaine does not appear to be associated with elevated blood pressure in young children.


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