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Clinical Pediatrics
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Prevalence and Correlates of Blood Pressure Elevation in Children with Guillain-Barre Syndrome

W. O. Cooper, MD, MPH

Division of General Pediatrics, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN

S. R. Daniels, MD, PhD

Pediatric Cardiology, University of Cincinnati College of Medicine and the Children's Hospital Research Foundation, Cincinnati, OH

J. M. H. Loggie, MD

Clinical Pharmacology, Department of Paediatrics, University of Cincinnati College of Medicine and the Children's Hospital Research Foundation, Cincinnati, OH

While there have been case reports describing blood pressure elevation in adults and children with Guillain-Barre syndrome (GBS), no previous systematic study has explored the prevalence of hypertension in children with this condition. In a retrospective review, blood pressure elevation was seen in 20 of 30 (66.7%) patients with GBS admitted to a children's hospital during a 10-year period. There was a significant correlation between highest GBS stage and deviation of systolic blood pressure from age- and gender-specific norms (r=0.93, p<0.05). Since blood pressure may be markedly elevated in GBS, the clinician caring for a child with this condition should be aware of this complication.

Clinical Pediatrics, Vol. 37, No. 10, 621-624 (1998)
DOI: 10.1177/000992289803701005
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