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Clinical Pediatrics
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*Epilepsy
*Seizures
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Reviews

A Review of the Newer Antiepileptic Drugs and the Ketogenic Diet

Todd F. Barron, MD

Sarah L. Hunt, MS, CRNP

Department of Pediatrics, Division of Pediatric Neurology, The Milton S. Hershey Medical Center, The Pennsylvania State University, College of Medicine, Hershey, PA

Since 1994, three new antiepileptic drugs, felbamate, lamotrigene, and gabapentin, have been released for the treatment of epilepsy. The present paper provides an overview of these three drugs and reviews their potential uses in pediatric epilepsy even though felbamate is the only one with an approved use in children. Topiramate and vigabatrin, which are under investigation, are briefly reviewed. In addition, a discussion of the ketogenic diet is included because of its recent publicity. Patient examples included provide clinical illustrations for the reader.

Clinical Pediatrics, Vol. 36, No. 9, 513-521 (1997)
DOI: 10.1177/000992289703600904
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F. Lefevre and N. Aronson
Ketogenic Diet for the Treatment of Refractory Epilepsy in Children: A Systematic Review of Efficacy
Pediatrics, April 1, 2000; 105(4): 46e - 46.
[Abstract] [Full Text]