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Clinical Pediatrics
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A Lamb-Meat-Based Formula for Infants Allergic to Casein Hydrolysate Formulas

Batia Weisselberg, M.D.

Department of Pediatric Gastroenterology and Nutrition, New England Medical Center Hospital, and Tufts University School of Medicine, Boston, Massachussets

Yogesh Dayal, M.D.

Department of Pediatric Gastroenterology and Pathology, New England Medical Center Hospital, and Tufts University School of Medicine, Boston, Massachussets

John F. Thompson, M.D.

Department of Pediatric Gastroenterology and Nutrition, New England Medical Center Hospital, and Tufts University School of Medicine, Boston, Massachussets

Marcia S. Doyle, M.S., R.D.

Department of Pediatric Gastroenterology and Nutrition, New England Medical Center Hospital, and Tufts University School of Medicine, Boston, Massachussets

Boris Senior, M.D.

Department of Pediatric Gastroenterology and Pediatric Endocrinology, New England Medical Center Hospital, and Tufts University School of Medicine, Boston, Massachussets

Richard J. Grand, M.D.

Division of Pediatric Gastroenterology & Nutrition, New England Medical Center, 750 Washington Street (Box 213), Boston, MA 02111.

Ten infants with colitis due to milk protein allergy, presenting as hematochezia, whose symptoms did not resolve with the use of hydrolyzed cow-milk-based formulas, were treated with a modular lamb-meat-based formula (LOP). The patients were followed up for 3 months to 5 years. Prompt resolution of symptoms was achieved. In three patients, increased levels of creatinine and blood urea nitrogen and mild metabolic acidosis were noted, all returning to normal after the protein intake was lowered. All patients had normal growth. Seven patients were able to tolerate cow milk protein or soy at age 9-15 months. The LOP formula is well tolerated and is a safe alternative formula for infants allergic to cow milk hydrolysate formula.

Clinical Pediatrics, Vol. 35, No. 10, 491-495 (1996)
DOI: 10.1177/000992289603501002
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