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Clinical Pediatrics, Vol. 33, No. 9, 517-524 (1994)
DOI: 10.1177/000992289403300902

Neuropsychological Impairment in Children With Sickle Cell Anemia and Cerebrovascular Accidents

Morris J. Cohen

Department of Neurology, Medical College of Georgia, Department of Pediatrics, Medical College of Georgia, Department of Psychiatry, Medical College of Georgia, Augusta, Georgia

Walter B. Branch

Department of Neurology, Medical College of Georgia

Virgil C. McKie

Department of Pediatrics, Medical College of Georgia

Robert J. Adams

Department of Neurology, Medical College of Georgia

Neuropsychological functioning of children with sickle cell anemia (HbSS) who have experienced a single stroke has not been extensively investigated. In this study, the neuropsychological functioning of 10 children with HbSS who were receiving transfusion therapy following stroke with no identifiable recurrence was examined. The patients were subgrouped into children with only left hemisphere stroke (LCI), N = 4, and those with only right hemisphere stroke (RCI), N = 6. Results indicated that these youngsters experienced significant impairments of cognitive functioning following stroke. It was found that the LCI and RCI children tended to perform more like adult stroke patients than what has been typically reported in children with infantile hemiplegia. These findings support the need for periodic neuropsychological evaluation following stroke in order to identify patterns of higher cortical dysfunction and assist in the development of appropriate rehabilitation and special education programs. Further, pediatricians, child neurologists, and psychologists who care for these children must act as strong advocates on their behalf in order to ensure that they receive appropriate rehabilitation and the special education services necessary for maximal recovery and future educational success.


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