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Neurodevelopment in Pediatric HIV Infection

The Use of CAT/CLAMS

Department of Pediatrics University of Maryland School of Medicine Baltimore, Maryland

Vicki J. Tepper

Department of Pediatrics University of Maryland School of Medicine Baltimore, Maryland

Debra Houck

Department of Pediatrics University of Maryland School of Medicine Baltimore, Maryland

Cathleen J. McGrath

Department of Pediatrics University of Maryland School of Medicine Baltimore, Maryland

Christine Thompson

Department of Pediatrics University of Maryland School of Medicine Baltimore, Maryland

Pediatric neuro-AIDS may be the first clinical manifestation of HIV infection in children born to HIV infected mothers. As part of the neurodevelopmental examination of children, the Clinical Adaptive Test/Clinical Linguistic and Auditory Milestone Scale (CAT/CLAMS) was investigated as a tool for pediatricians to use to monitor the development of children at risk for HIV infection. The CAT/CLAMS was found to detect neurodevelopmental differences between HIV-infected and uninfected children at 12 and 18 months of age. Good correlations were found between the CAT/CLAMS and concurrently administered Bayley Scales of Infant Development. These findings suggest that the CAT/CLAMS should be considered as a part of the neurodevelopmental examination of children at risk for pediatric neuro-AIDS.

Clinical Pediatrics, Vol. 33, No. 7, 416-420 (1994)
DOI: 10.1177/000992289403300707


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