Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here for more information

Sign In to gain access to subscriptions and/or personal tools.
Clinical Pediatrics
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Bonadio, W. A.
Right arrow Articles by Smith, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bonadio, W. A.
Right arrow Articles by Smith, D.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Efficacy of a Protocol to Distinguish Risk of Serious Bacterial Infection in the Outpatient Evaluation of Febrile Young Infants

William A. Bonadio, M.D.

4143 Beard Avenue South, Minneapolis, MN 55410, Children's Emergency Room, St. Paul Children's Hospital, St. Paul, Minnesota

Elizabeth Hagen, M.D.

Department of Pediatrics, The Medical College of Wisconsin, Children's Hospital of Wisconsin Milwaukee, Wisconsin

Jennifer Rucka, M.D.

Department of Pediatrics, The Medical College of Wisconsin, Children's Hospital of Wisconsin Milwaukee, Wisconsin

Kathleen shallow, M.D.

Department of Pediatrics, The Medical College of Wisconsin, Children's Hospital of Wisconsin Milwaukee, Wisconsin

Peggy Stommel, M.D.

Department of Pediatrics, The Medical College of Wisconsin, Children's Hospital of Wisconsin Milwaukee, Wisconsin

Douglas Smith, M.D.

Department of Pediatrics, The Medical College of Wisconsin, Children's Hospital of Wisconsin Milwaukee, Wisconsin

A study of 534 febrile infants ages 4 to 8 weeks evaluated for sepsis assessed the efficacy of the Milwaukee Protocol (MP) for selecting patients at low risk for serious bacterial infection (SBI) who might benefit from outpatient management. Two groups were compared: 1) Infants with uncompromised presentation (UP) who met all MP criteria received ceftriaxone 50 mg/kg and were discharged, then reevaluated within 24 hours. 2) Infants with compromised presentation (CP) who did not meet MP criteria were hospitalized for antibiotic therapy pending culture results. Of 391 CP patients, 23 (5.9%) had SBI; of 143 UP patients, 1 (0.7%) had SBI (P <.02). The MP criteria had a sensitivity of 96% and a 99% negative predictive value for distinguishing SBI outcome. The only UP patient with SBI was afebrile and had a negative repeat blood culture after 24 hours, and recovered with no complications. Managing UP infants as outpatients avoided 48 to 72 hours of hospitalization, decreasing health-care costs by an estimated total of $465,170.

Clinical Pediatrics, Vol. 32, No. 7, 401-404 (1993)
DOI: 10.1177/000992289303200703
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?