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Clinical Pediatrics, Vol. 31, No. 7, 409-412 (1992)
DOI: 10.1177/000992289203100706

Severe Mycoplasma Pneumonia in Young Children with Down Syndrome

Shari L. Orlicek, M.D.

Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City

Michael S. Walker, M.D.

Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City

Thomas L. Kuhls, M.D.

Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City

Three young children with Down syndrome developed fever, cough, wheezing, irritability, and tachypnea. They had bilateral infiltrates on their chest radiographs and developed respiratory distress, which required their hospitalization. Laboratory studies suggested that the children had mycoplasma pneumonia. These children may have experienced severe mycoplasma infections early in life because of their Down syndrome-associated immune abnormalities. When young children with Down syndrome develop pneumonia, physicians should consider Mycoplasma pneumoniae as the possible etiologic agent.


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