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A Treatment Program for Adolescents With Phenylketonuria

Department of Nutrition and Medical Dietetics, University of Illinois at Chicago, Room 650, M/C 518, 1919 W. Taylor St., Chicago, IL 60612

Kimberlee Michals, Ph.D., R.D.

Department of Nutrition and Medical Dietetics, University of Illinois at Chicago, The Research Institute, Miami Children's Hospital, Miami, Florida

Reuben Matalon, M.D., Ph.D.

Department of Nutrition and Medical Dietetics, University of Illinois at Chicago, The Research Institute, Miami Children's Hospital, Miami, Florida

Patricia Langenberg, Ph.D.

Department of Epidemiology, University of Maryland, Baltimore

Savitri Kamath, Ph.D., R.D.

Department of Nutrition and Medical Dietetics, University of Illinois at Chicago

A treatment program for adolescents with phenylketonuria (PKU) , incorporating education, goal-setting, self-monitoring, contracts, and rewards, was evaluated by measuring knowledge of PKU, blood phenylalanine concentrations, and health locus of control (LOC) before and after participation in the program. Of the 16 subjects, seven subjects successfully completed the program by achieving behavioral goals. These subjects increased their knowledge of PKU and decreased their blood phenylalanine concentrations, but the nine nonsuccessful subjects did not. There was no significant change in LOC scores for either group. There was a significant relationship between baseline blood phenylalanine levels and success with the program. Therefore, this pilot study demonstrates that adolescents who have already achieved some measure of metabolic control can be expected to be most successful with this program and realize the greatest benefits from it in the form of increased knowledge of PKU and even better metabolic control.

Clinical Pediatrics, Vol. 31, No. 6, 331-335 (1992)
DOI: 10.1177/000992289203100603


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