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Clinical Pediatrics, Vol. 31, No. 5, 299-301 (1992)
DOI: 10.1177/000992289203100507

Low-Dose DDAVP in Nocturnal Enuresis

David W. Key, M.D.

Section of Urology Department of Surgery University of Michigan Medical Center Ann Arbor, Michigan

David A. Bloom, M.D.

Section of Urology Department of Surgery University of Michigan Medical Center Ann Arbor, Michigan

Jill Sanvordenker, R.N.

Section of Urology Department of Surgery University of Michigan Medical Center Ann Arbor, Michigan

A five-year experience with the vasopressin analogue desmopressin acetate (DDAVP) for nocturnal enuresis is described in 59 children. The initial starting dose of 5 µg at bedtime is lower than that reported in other series. Eighty-one percent of patients required 10 µg or less to achieve improvement or resolution of bedwetting.


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Risk/Benefit Ratio in Enuresis Therapy
Clinical Pediatrics, May 1, 1992; 31(5): 308 - 310.
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