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DOI: 10.1177/000992289002900504 Chemoprophylaxis with Oral Trimethoprim-sulfamethoxazole In Otitis MediaRelevance of Hematologic AbnormalitiesDepartment of Otolaryngology, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114 The author reviewed the potential risks of trimethoprim-sulfamethoxazole (TMP-SMX) treatment in children so that a more educated decision can be made in the choice of a prophylactic drug for recurrent acute otitis media, particularly in the penicillin (ampicillin, amoxicillin) allergic child.
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