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Clinical Pediatrics
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Childhood Cancer Survivors: Attained Adult Heights

Compared with Sibling Controls

Grace E. Holmes, MD

Room 2016, Building 48, University of Kansas Medical Center, Kansas City, KS 66103

Frederick F. Holmes, MD

Department of Medicine, University of Kansas Medical Center

Ariel B. Baker, BS

Cancer Data Service, University of Kansas Medical Center

Ruth S. Hassanein, PhD

Department of Biometry, University of Kansas Medical Center, Kansas City, Kansas

As part of a large collaborative study, the authors administered a pretested questionnaire to 62 childhood and adolescent cancer survivors and 62 same-sex sibling controls. The authors requested information regarding attained adult height on the questionnaire. Mean adult height of survivors (172.2 cm) was less than that of controls (174.1 cm), at a borderline significant difference of p = 0.0757. Multivariate analysis examined four potential, independent variables as possible predictors of this difference. The presence of brain tumor (vs. nonbrain tumor) (p < .0001) and diagnosis at an early age (≤ 8 years vs. 9-15 years) (p = .05) were factors significantly related to the differential; sex of patient and type of therapy were not. Our findings thus identify malignancy site and age at diagnosis as important predictors of adult height in childhood and adolescent cancer survivors.

Clinical Pediatrics, Vol. 29, No. 5, 268-272 (1990)
DOI: 10.1177/000992289002900503
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