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Transient Lymphoblastosis and Thrombocytopenia in Gianotti-Crosti Syndrome

Department of Pediatrics, University of Connecticut Health Center, Farmington, Connecticut

Steven J. Weisman

Divisions of Hematology/Oncology, University of Connecticut Health Center, Farmington, Connecticut

K. Lynn Cates

Infectious Disease, University of Connecticut Health Center, Farmington, Connecticut

Gianotti-Crosti Syndrome, or papular acrodermatitis of childhood, represents a characteristic rash that is irregularly associated with hepatitis B infection. The authors report papular acrodermatitis in a 10-month-old child with leukopenia, thrombocytopenia, circulating lymphoblasts, and acute anicteric hepatitis B. Physical examination revealed a densely distributed papular rash on the patient's extremities and face and neck, but not on his trunk, buttocks, palms, or soles. Laboratory investigation revealed a normal bone marrow and positive hepatitis B serology. This case reinforces the fact that hematologic findings should not dissuade the work-up of papular acrodermatitis for hepatitis B or other less commonly associated viruses.

Clinical Pediatrics, Vol. 29, No. 3, 185-187 (1990)
DOI: 10.1177/000992289002900310


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