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Thrombocytopenia Absent Radius Syndrome Associated with Renal Insufficiency

The Johns Hopkins University School of Medicine and Hospital, Baltimore, Maryland

Sharon McGrath, MD

The Johns Hopkins University School of Medicine and Hospital, Baltimore, Maryland

William Zinkham, MD

The Johns Hopkins University School of Medicine and Hospital, Baltimore, Maryland

Thrombocytopenia absent radius (TAR) syndrome, associated with small, echogenic kidneys and subsequent end-stage renal disease, was seen in a full-term newborn. In this infant, renal insufficiency may have increased the known risk of bleeding that is associated with TAR syndrome. Renal abnormalities and dysfunction are unusual in TAR syndrome. When they are present, however, treatment with frequent transfusions and early dialysis may be necessary to prevent serious and life-threatening hemorrhagic episodes.

Clinical Pediatrics, Vol. 29, No. 3, 182-184 (1990)
DOI: 10.1177/000992289002900309


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