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Clinical Pediatrics
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Purpura Fulminans

A Case for Heparin Therapy

Peter J. Chenaille, MD

Department of Hematology-Oncology, St. Jude Children's Research Hospital, Box 318, Memphis, TN 38101-0318

Marc E. Horowitz, MD

A 6.5-year-old boy developed purpura fulminans. He had no evidence of congenital protein C deficiency. He responded readily to heparin therapy with resolution of his coagulopathy. The coagulopathy resumed rapidly after heparin therapy was interrupted to allow for surgical procedures. Despite correction of his coagulopathy with heparin, surgical amputation of his leg was necessary because of inadequate perfussion.

Clinical Pediatrics, Vol. 28, No. 2, 95-98 (1989)
DOI: 10.1177/000992288902800208
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