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Clinical Pediatrics
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Extreme Hyperpyrexia in Childhood

Presentation Similar to Hemorrhagic Shock and Encephalopathy

William B. Caspe, MD

Department of Pediatrics, Bronx Lebanon Hospital Center, 1650 Grand Concourse, Bronx, NY 10457

Anne T. Nucci, MD

Department of Pediatrics, Bronx Lebanon Hospital Center and the Albert Einstein College of Medicine, Bronx, New York

Sangho Cho, MD

Department of Pathology, Bronx Municipal Hospital Center, and the Albert Einstein College of Medicine, Bronx, New York

The authors report the cases of five previously well children, aged 8 to 33 months, who were seen over a 14-year period, with admission temperatures in excess of 42.0°C (107.6°F). Four of the patients died. Each child had a similar clinical illness in which the hyperpyrexia played a critical role. Negative blood, cerebrospinal fluid, and stool cultures excluded bacterial sepsis as a possible etiology. This illness is similar, if not identical, to the newly described syndrome of hemorrhagic shock and encephalopathy (HSES) reported in European and American infants.

Clinical Pediatrics, Vol. 28, No. 2, 76-80 (1989)
DOI: 10.1177/000992288902800204
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This article has been cited by other articles:


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 Arch Pediatr Adolesc MedHome page
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