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Clinical Pediatrics
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Splenic Infarction at Low Altitude in a Child with Hemoglobin S-C Disease

Carlos S. Alvarado, MD

Department of Pediatrics, Division of Hematology/Oncology, Emory University School of Medicine, Atlanta, Georgia

Brad Wyly, MD

Department of Radiology, Emory University School of Medicine, Atlanta, Georgia

Iris Buchanan, MD

Department of Pediatrics, Division of Hematology/Oncology, Emory University School of Medicine, Atlanta, Georgia

William A. Fajman, MD

Department of Radiology, Emory University School of Medicine, Atlanta, Georgia

We describe a 15-year-old black boy with hemoglobin S-C disease living in Atlanta (altitude 1,034 ft), with no prior history of aircraft or mountain travel, who developed splenic infarction. The clinical picture was characterized by severe left upper quadrant abdominal pain, fever, splenomegaly, and hematologic and scintigraphic evidence of functional asplenia. The diagnosis was suggested by liver/spleen scintigraphy and further confirmed by ultrasonography and computerized tomography (CT) of the spleen. Treatment consisted of analgesics, intravenous fluids, and short-term antibiotic therapy. The child recovered without sequelae.

Clinical Pediatrics, Vol. 27, No. 8, 396-399 (1988)
DOI: 10.1177/000992288802700809
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