This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Sasidharan, P. Search for Related Content PubMed PubMed Citation Articles by Sasidharan, P. Social Bookmarking                         What's this?

Postnatal IgG Levels in Very-low-birth-weight Infants

Preliminary Observations

Department of Pediatrics, the Neonatology Section, Milwaukee County Medical Complex, Medical College of Wisconsin, Milwaukee, Wisconsin

We studied the gammaglobulin levels (IgG) postnatally, serially, in 42 infants of very low birthweight (mean ± SD 971 ± 225 g) with gestational ages ranging from 23 to 31 weeks. Eighteen infants (42.8%) had IgG levels of less than 100 mg/dl by a mean postnatal age of 71.2 ±16 days. The lowest level was 22 mg/dl in an infant whose birthweight was 700 g. Sixteen of the 42 infants (mean birthweight 946.8 ± 260 g) also had cord blood IgG levels determined. The mean cord blood IgG was 413.5 ± 163 mg/dl. This had dropped to 140.3 ± 87 mg/dl by 57 days, a drop of 66 percent. As expected, the lowest IgG levels postnatally was a reflection of the degree of prematurity and the length of postnatal age. Such extremely low levels of IgG have not been reported previously.

Clinical Pediatrics, Vol. 27, No. 6, 271-274 (1988)
DOI: 10.1177/000992288802700601


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?