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Clinical Pediatrics, Vol. 26, No. 9, 459-463 (1987)
DOI: 10.1177/000992288702600905

Acquired Coagulation Inhibitor in Association With Rocky Mountain Spotted Fever

With a Review of Other Acquired Coagulation Inhibitors

Philip G. Scimeca

Department of Pediatrics, Division of Hematology-Oncology, North Shore University Hospital, Manhasset, NY 11030

Mark E. Weinblatt

Department of Pediatrics, Division of Hematology-Oncology, North Shore University Hospital, Manhasset, NY 11030

Joseph A. Kochen

Department of Pediatrics, Division of Hematology-Oncology, North Shore University Hospital, Manhasset, NY 11030

An acutely ill 4-year-old girl with Rocky Mountain spotted fever (RMSF) was found to have a coagulation inhibitor. This child had no serious bleeding manifestations and minimal hemorrhagic skin manifestations despite severe RMSF, concurrent thrombocytopenia, as well as the coagulation inhibitor. Hemostatic abnormalities that occur with RMSF as well as other infectious illnesses associated with coagulation inhibitors are reviewed.


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